Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA5A | P35218 | 2/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | OGT | O15294 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068164 | 0.93 | PTGS2 (0.62) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL16220811 | 0.91 | PTGS2 (0.72) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL26628312 | 0.87 | PTGS2 (0.67) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL1119554 | 0.87 | PTGS2 (0.66) | FLT3PTGS2CA1CA2CA5A | |
| Bromide SCHEMBL6256547 | 0.85 | PTGS2 (0.64) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL23557718 | 0.83 | PTGS2 (0.63) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL18031100 | 0.83 | PTGS2 (0.63) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL1849056 | 0.83 | MIF (0.74) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL12450544 | 0.83 | CA2 (0.61) | FLT3PTGS2CA1CA2CA5A | |
| SCHEMBL2053754 | 0.83 | CA2 (0.61) | FLT3PTGS2CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563659-B | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2020-08-21 | — | — | CN | disclosed |
| CN-110563659-A | Method for preparing 1,2, 3-triazole compound by heterogeneous copper catalysis in one pot | 浙江工业大学 | 2019-12-13 | — | — | CN | disclosed |