Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MLNR | O43193 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553699 | 0.97 | MAPT (0.57) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL7885154 | 0.95 | MAPT (0.56) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL7885152 | 0.94 | MAPT (0.54) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL22966227 | 0.88 | ALDH1A1 (0.54) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL28443844 | 0.87 | TBXA2R (0.52) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL4231911 | 0.86 | ALDH1A1 (0.54) | MEN1KMT2AMAPTTSHRCYP3A4 | |
| SCHEMBL4238016 | 0.85 | KMT2A (0.71) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL4235361 | 0.85 | ALDH1A1 (0.51) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL22966277 | 0.85 | TBXA2R (0.53) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL16023861 | 0.85 | HSPB1 (0.71) | MEN1KMT2AMAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452167-B | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-110452167-A | Quinoline derivatives and its preparation method and application | DONGGUAN HEC PESTICIDE RES AND DEVELOPMENT CO LTD | 2019-11-15 | — | — | CN | disclosed |