SCHEMBL28337654

SCHEMBL28337654

Nc1ccc(OC=C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.47
RAB9A P51151 3/20 0.40
MAOB P27338 3/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
NPC1 O15118 2/20 0.39
NLRP3 Q96P20 1/20 0.39
TDP1 Q9NUW8 5/20 0.38
CYP3A4 P08684 4/20 0.38
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
CYP19A1 P11511 2/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
NCOA1 Q15788 1/20 0.37
NCOA3 Q9Y6Q9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931244 0.86 PDE4A (0.42) L3MBTL1TDP1ALDH1A1TSHRCYP19A1
SCHEMBL28880029 0.80 MAOB (0.52) MAOARAB9AMAOBMAPTGAA
SCHEMBL10606928 0.77 CYP1B1 (0.40) MAOARAB9AMAOBSMN1; SMN2MEN1
SCHEMBL28726975 0.75 ALDH1A1 (0.37) MAOAMAOBMAPTGAASMN1; SMN2
SCHEMBL1827690 0.74 ALDH1A1 (0.41) MAPTL3MBTL1TDP1CYP3A4ALDH1A1
SCHEMBL4838757 0.73 CYP1B1 (0.46) MAOARAB9AMAOBMAPTSMN1; SMN2
SCHEMBL4838747 0.73 CYP1B1 (0.46) MAOARAB9AMAOBMAPTSMN1; SMN2
SCHEMBL8148109 0.73 CYP1B1 (0.46) MAOARAB9AMAOBMAPTSMN1; SMN2
SCHEMBL9351934 0.72 CYP1B1 (0.42) MAOARAB9AMAPTSMN1; SMN2MEN1
SCHEMBL10517665 0.71 ALDH1A1 (0.44) MAOARAB9AMAOBMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384378-A Photosensitive polyamic acid ester resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2024-01-12 CN claimed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 CN claimed
CN-109852330-B 3, 5-diaminobenzoic acid type silicon-containing adhesive and preparation method thereof 东华大学 2022-01-11 CN claimed
CN-110591293-A Carbon fiber cable core pultrusion resin and preparation method thereof 东华大学 2019-12-20 CN claimed
CN-112226081-B Laser sensitization resin composition, preparation method and application thereof 中国石油化工股份有限公司 2023-05-02 CN disclosed
CN-114249911-A Fiber-reinforced polyimide-based composite material and preparation method thereof 南京工业大学 2022-03-29 CN disclosed
CN-114015044-A Colorless transparent polyimide resin film and preparation method thereof 山东中柔新材料有限公司 2022-02-08 CN disclosed
CN-109852330-B 3, 5-diaminobenzoic acid type silicon-containing adhesive and preparation method thereof 东华大学 2022-01-11 CN disclosed
CN-110591293-A Carbon fiber cable core pultrusion resin and preparation method thereof 东华大学 2019-12-20 CN disclosed