SCHEMBL1827690

SCHEMBL1827690

C(OC=C(c1ccccc1)c1ccccc1)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
CYP19A1 P11511 2/20 0.41
CYP11B2 P19099 2/20 0.41
CYP2C19 P33261 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
F2 P00734 2/20 0.40
LMNA P02545 1/20 0.40
TSHR P16473 3/20 0.39
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931244 0.82 PDE4A (0.42) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1
SCHEMBL28728329 0.79 TSHR (0.44) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1
SCHEMBL14354268 0.77 ALDH1A1 (0.38) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1
SCHEMBL10419768 0.74 MAOA (0.45) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1
SCHEMBL28337654 0.74 MAOA (0.47) ALDH1A1CYP19A1CYP2C19L3MBTL1CYP1A2
SCHEMBL2349525 0.74 MEN1 (0.47) ALDH1A1NPSR1TDP1F2LMNA
SCHEMBL10437667 0.74 CYP19A1 (0.39) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1
SCHEMBL660285 0.74 MTNR1A (0.39) ALDH1A1L3MBTL1LMNATSHRCES2
SCHEMBL6548505 0.74 TDP1 (0.42) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1
SCHEMBL88322 0.73 ALDH1A1 (0.46) ALDH1A1CYP19A1CYP11B2CYP2C19L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252712-B2 Polymer dispersant addition to fuel cell electrode inks for improved manufacturability GM Global Technology Operations LLC (US) 2012-08-28 US disclosed
US-20110117472-A1 POLYMER DISPERSANT ADDITION TO FUEL CELL ELECTRODE INKS FOR IMPROVED MANUFACTURABILITY GM GLOBAL TECHNOLOGY OPERATIONS, INC. (US) 2011-05-19 US disclosed