SCHEMBL28337804

SCHEMBL28337804

CC(C)(C)c1c(F)ccc(Br)c1F

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.31
KCNH2 Q12809 2/20 0.31
KDM1B Q8NB78 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2063973 0.83 MEN1 (0.35)
SCHEMBL12871808 0.80 CES2 (0.37)
SCHEMBL12678823 0.79 NQO2 (0.36)
SCHEMBL29396883 0.79 KDM1A (0.31) KDM1AKCNH2KDM1B
SCHEMBL16652774 0.79 KDM1A (0.31) KDM1AKCNH2KDM1B
SCHEMBL20780624 0.74 PTGS1 (0.32)
SCHEMBL10262020 0.74 ACHE (0.33)
SCHEMBL14131096 0.73 KMT2A (0.33)
SCHEMBL10256478 0.73 HTT (0.32)
SCHEMBL14200094 0.70 HTR2A (0.39) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461890-A BIS-BIPHENYL-PHENOXY CATALYSTS FOR OLEFIN POLYMERIZATION DOW GLOBAL TECHNOLOGIES LLC 2019-11-15 CN disclosed