Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12369722 | 0.83 | DPP4 (0.52) | DPP4PTGS1PTGS2NOTUMMAOA | |
| SCHEMBL30740915 | 0.81 | MAOA (0.63) | DPP4ALKNOTUMMAOAL3MBTL1 | |
| SCHEMBL25920363 | 0.81 | ALK (0.42) | ALKNOTUMMAOAL3MBTL1KDM1A | |
| SCHEMBL12395303 | 0.81 | JAK2 (0.50) | DPP4PTGS1PTGS2NOTUMMAOA | |
| SCHEMBL28340294 | 0.80 | NOTUM (0.68) | DPP4PTGS1PTGS2NOTUMMAOA | |
| SCHEMBL28340291 | 0.78 | CYP2A6 (0.45) | DPP4PTGS1PTGS2CYP2A6MIF | |
| SCHEMBL18377714 | 0.74 | CYP2A6 (0.51) | DPP4PTGS1PTGS2L3MBTL1CYP2A6 | |
| Hydrochloric Acid SCHEMBL30223640 | 0.74 | GRIN1 (0.56) | ALKNOTUMKDM1ACA12CA9 | |
| SCHEMBL24497357 | 0.73 | CYP2A6 (0.59) | CYP2A6CACNA2D1EPHX2PRMT6ELANE | |
| SCHEMBL31753471 | 0.73 | PTGS1 (0.44) | DPP4PTGS1PTGS2MAP3K8KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590885-A | 20-substituted-5-O-mycaminosyl-tylonolide derivatives | 郑州大学 | 2019-12-20 | — | — | CN | disclosed |