SCHEMBL30740915

SCHEMBL30740915

CNCc1cn(-c2ccncc2)nn1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.63
NOTUM Q6P988 7/20 0.45
DPP4 P27487 1/20 0.45
ALK Q9UM73 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
FLT3 P36888 1/20 0.43
KDM1A O60341 2/20 0.43
MAOB P27338 1/20 0.42
P2RX7 Q99572 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
RXRA P19793 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2B Q13224 1/20 0.41
MIF P14174 4/20 0.41
CD74 P04233 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28337945 0.81 DPP4 (0.49) MAOANOTUMDPP4ALKL3MBTL1
SCHEMBL25920363 0.80 ALK (0.42) MAOANOTUMALKL3MBTL1KDM1A
SCHEMBL16271175 0.78 MAOA (0.65) MAOANOTUMDPP4L3MBTL1FLT3
SCHEMBL16479597 0.75 MIF (0.59) NOTUMP2RX7MIF
SCHEMBL17795447 0.74 MIF (0.58) P2RX7MIF
SCHEMBL16991685 0.73 MAOA (0.63) MAOANOTUMDPP4L3MBTL1FLT3
SCHEMBL22358471 0.73 NOTUM (0.65) NOTUML3MBTL1P2RX7KDM4EMAPT
SCHEMBL28206334 0.73 RXRA (0.41) ALKKDM4ERXRAGRIN1GRIN2B
Hydrochloric Acid SCHEMBL30223640 0.73 GRIN1 (0.56) NOTUMALKKDM1ARXRAGRIN1
SCHEMBL13527037 0.72 MIF (0.43) NOTUMALKP2RX7RXRAGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
CN-119546566-A FTO inhibitors 瑞璞鑫(苏州)生物科技有限公司 2025-02-28 CN disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 MAOA 391/4885NOTUM 1276/4885DPP4 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.