SCHEMBL28338201

SCHEMBL28338201

Nc1cc(C(F)(F)F)ccc1N1CCN(c2ccc(C(F)(F)F)cc2N)CC1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.78
KDM4E B2RXH2 4/20 0.78
LMNA P02545 2/20 0.78
PKM P14618 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.50
HTT P42858 2/20 0.47
GAA P10253 1/20 0.47
POLB P06746 1/20 0.46
S100B P04271 1/20 0.46
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
DHFR P00374 2/20 0.44
CFTR P13569 1/20 0.44
MAPT P10636 4/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
AADAT Q8N5Z0 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5494223 0.93 ALDH1A1 (0.73) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL330331 0.93 ALDH1A1 (0.73) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL1048147 0.92 KDM4E (0.68) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL997022 0.91 ALDH1A1 (0.71) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL1110554 0.91 ALDH1A1 (0.71) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL1110535 0.91 ALDH1A1 (0.71) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL1110503 0.91 ALDH1A1 (0.71) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL4445185 0.89 ALDH1A1 (0.64) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL30063002 0.89 ALDH1A1 (0.64) ALDH1A1KDM4ELMNAPKML3MBTL1
SCHEMBL23851217 0.88 ALDH1A1 (0.72) ALDH1A1KDM4ELMNAPKML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN claimed
CN-113336998-B Preparation method of benzocyclobutene side group cross-linked polyimide film with low dielectric and low heat conduction and micropores 中国科学院过程工程研究所 2022-10-21 CN claimed
CN-113336998-A Preparation method of benzocyclobutene side group cross-linked polyimide film with low dielectric and low heat conduction and micropores 中国科学院过程工程研究所 2021-09-03 CN claimed
CN-110606951-B Semi-aromatic polyimide, preparation method and application thereof, and gas separation membrane comprising semi-aromatic polyimide 中国科学院过程工程研究所 2020-11-13 CN claimed
CN-110606951-A Semi-aromatic polyimide, preparation method and application thereof, and gas separation membrane comprising semi-aromatic polyimide 中国科学院过程工程研究所 2019-12-24 CN claimed
US-12312448-B2 Polyimide microparticles XEROX CORPORATION (US) 2025-05-27 US disclosed
CN-115521410-A Preparation method of perfluoropolymer emulsion, perfluoroelastomer and preparation method of perfluoroelastomer 上海森崚半导体科技有限公司 2022-12-27 CN disclosed
CN-115322398-A Polyimide fine particles 施乐公司 2022-11-11 CN disclosed
CN-113336998-B Preparation method of benzocyclobutene side group cross-linked polyimide film with low dielectric and low heat conduction and micropores 中国科学院过程工程研究所 2022-10-21 CN disclosed
CN-113336998-A Preparation method of benzocyclobutene side group cross-linked polyimide film with low dielectric and low heat conduction and micropores 中国科学院过程工程研究所 2021-09-03 CN disclosed
CN-110606951-B Semi-aromatic polyimide, preparation method and application thereof, and gas separation membrane comprising semi-aromatic polyimide 中国科学院过程工程研究所 2020-11-13 CN disclosed
CN-110606951-A Semi-aromatic polyimide, preparation method and application thereof, and gas separation membrane comprising semi-aromatic polyimide 中国科学院过程工程研究所 2019-12-24 CN disclosed