Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 8/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837092 | 0.86 | S1PR3 (0.42) | S1PR3ACACBMAPK1POLQP2RX3 | |
| SCHEMBL2833085 | 0.84 | MAPK1 (0.38) | S1PR3ACACBMAPK1P2RX3P2RX2 | |
| SCHEMBL2836777 | 0.83 | ACACB (0.38) | S1PR3ACACBMAPK1POLQP2RX3 | |
| SCHEMBL2836299 | 0.82 | S1PR3 (0.43) | S1PR3ACACBMAPK1POLQP2RX3 | |
| SCHEMBL2834066 | 0.80 | S1PR3 (0.43) | S1PR3ACACBMAPK1P2RX3P2RX2 | |
| SCHEMBL2837082 | 0.79 | MAPK1 (0.38) | S1PR3ACACBMAPK1 | |
| SCHEMBL2836827 | 0.79 | S1PR3 (0.38) | S1PR3ACACBMAPK1P2RX3P2RX2 | |
| SCHEMBL2837646 | 0.78 | S1PR3 (0.39) | S1PR3ACACBMAPK1 | |
| SCHEMBL2835006 | 0.77 | S1PR3 (0.42) | S1PR3MAPK1P2RX3P2RX2 | |
| SCHEMBL2832253 | 0.76 | MAPK1 (0.41) | S1PR3MAPK1P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210592-A1 | AMINES OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | HOFFMANN-LA ROCHE, INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210592-A1 | AMINES OR AMINO ALCOHOLS AS GLYT1 INHIBITORS | GFPT1, CEPT1, SLC18A2 | S1PR3 2311/4885ACACB 996/4885MAPK1 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.