SCHEMBL28338609

SCHEMBL28338609

C=Cc1ccc(C(C)CO[SiH3])cc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
TSHR P16473 1/20 0.32
TYR P14679 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699213 0.83 ALDH1A1 (0.42) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL31190092 0.77 ALDH1A1 (0.37) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL11517329 0.76 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL716407 0.76 ALDH1A1 (0.48) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL2468494 0.76 TAS1R3 (0.42) ALDH1A1TAS1R3TAS1R1TSHR
SCHEMBL2467595 0.75 ALDH1A1 (0.46) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL3671591 0.75 ALDH1A1 (0.46) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL220825 0.75 ALDH1A1 (0.46) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4
SCHEMBL6268405 0.74 TAAR1 (0.52) ALDH1A1TRPA1
SCHEMBL5024850 0.73 TAS1R3 (0.46) ALDH1A1TAS1R3TAS1R1CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN claimed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
CN-117209673-B Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2024-04-26 CN disclosed
CN-117209673-A Flame-retardant low-temperature toughening synergistic anti-dripping agent and preparation method thereof 铨盛聚碳科技股份有限公司 2023-12-12 CN disclosed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN disclosed
CN-110627974-A High-heat-resistance phosphorus-silicon flame retardant, and preparation method and application thereof 铨盛聚碳科技股份有限公司 2019-12-31 CN disclosed