Fluoride

Fluoride

SCHEMBL28338906

CCCC[PH](CCCC)(CCCC)CCCC.F.F.F.F.F.F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.43
LMNA P02545 3/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 5/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.32
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 4/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL3413397 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL2114927 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL9615258 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL28465810 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL126217 0.96 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL126216 0.96 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL51248 0.96 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
Bromide SCHEMBL2551829 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Bromide SCHEMBL302421 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Butane SCHEMBL16949835 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115220303-A Photosensitive resin composition and display device comprising same 株式会社东进世美肯 2022-10-21 CN disclosed
CN-110546183-A Composition for encapsulating organic electronic components LG CHEMICAL LTD 2019-12-06 CN disclosed