Fluoride

Fluoride

SCHEMBL9615258

CCCC[PH](CCCC)(CCCC)CCCC.F.F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.43
LMNA P02545 3/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 5/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.32
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 4/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL3413397 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL28338906 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL2114927 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL28465810 1.00 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL126217 0.96 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
Fluoride SCHEMBL126216 0.96 TSHR (0.40) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL51248 0.96 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
Bromide SCHEMBL2551829 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Bromide SCHEMBL302421 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Butane SCHEMBL16949835 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186433-A Polyether-b-polyacrylate block copolymer and preparation method thereof 大连理工大学 2023-12-08 CN claimed
JP-4124195-A None JP disclosed
CN-118253469-A Laminate and method for producing same 株式会社东进世美肯 2024-06-28 CN disclosed
CN-114588939-B Catalyst and method for preparing iminooxadiazinedione-containing polyisocyanate 万华化学集团股份有限公司 2024-05-03 CN disclosed
CN-117903425-A Multifunctional reactive surfactant and preparation method thereof 常熟耐素生物材料科技有限公司 2024-04-19 CN disclosed
CN-117186433-A Polyether-b-polyacrylate block copolymer and preparation method thereof 大连理工大学 2023-12-08 CN disclosed
CN-115141335-B Preparation method of low-viscosity polyisocyanate composition 万华化学集团股份有限公司 2023-08-11 CN disclosed
CN-114539508-B Low-viscosity polyisocyanate composition for improving water dispersibility 万华化学集团股份有限公司 2023-05-30 CN disclosed
CN-116063658-A Preparation method of isocyanate composition 万华化学集团股份有限公司 2023-05-05 CN disclosed
CN-115141335-A Preparation method of low-viscosity polyisocyanate composition 万华化学集团股份有限公司 2022-10-04 CN disclosed
US-20190284226-A1 THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES THE SCRIPPS RESEARCH INSTITUTE 2019-09-19 US disclosed
US-20180194901-A1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS THE SCRIPPS RESEARCH INSTITUTE 2018-07-12 US disclosed
WO-2018102433-A1 THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES THE SCRIPPS RESEARCH INSTITUTE (US) 2018-06-07 WO disclosed
EP-3310795-A1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS The Scripps Research Institute (US) 2018-04-25 EP disclosed
WO-2016209920-A1 POLYMERIZATION OF SILYL- AND FLUORO-CONTAINING MONOMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2016-12-29 WO disclosed
JP-H04124195-A NEW METALLIC FLUORIDE COMPLEX OF QUATERNARY PHOSPHONIUM FLUORIDE, ITS PRODUCTION, FLUORINATING AGENT AND DESILYLATING AGENT HOKKO CHEM IND CO LTD 1992-04-24 JP disclosed
US-5008425-A Trifluoromethylation of carbonyl compounds ETHYL CORPORATION (US) 1991-04-16 US disclosed
EP-0336371-A2 Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-10-11 EP disclosed
US-4871877-A Gem-disubstituted cyclohexadienones and their production ETHYL CORPORATION (US) 1989-10-03 US disclosed
US-4845258-A Production of gem-disubstituted cyclohexadienones ETHYL CORPORATION (US) 1989-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190284226-A1 THIONYL TETRAFLUORIDE MODIFIED COMPOUNDS AND USES SFXN3, TST, SIRT3 TSHR 1094/4885LMNA 3980/4885THRB 3154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.