SCHEMBL28339162

SCHEMBL28339162

CC(NC(=O)CNC(=O)CN)C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 4/20 0.35
ALDH1A1 P00352 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TDP1 Q9NUW8 4/20 0.34
RECQL P46063 2/20 0.34
XBP1 P17861 2/20 0.34
MAPT P10636 4/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
POLB P06746 1/20 0.33
TERT O14746 1/20 0.33
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
GPR55 Q9Y2T6 1/20 0.32
PSMB5 P28074 2/20 0.32
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18913932 0.89 CA1 (0.39) NPSR1ALDH1A1HRH3TDP1RECQL
SCHEMBL19245755 0.89 CA1 (0.39) NPSR1ALDH1A1HRH3TDP1RECQL
SCHEMBL29233291 0.85 CTSK (0.40) CA1CA2CA7TERTCTSS
SCHEMBL23332499 0.84 NPSR1 (0.44) NPSR1ALDH1A1TDP1RECQLXBP1
SCHEMBL30029922 0.84 NPSR1 (0.44) NPSR1ALDH1A1TDP1RECQLXBP1
SCHEMBL29918164 0.81 NPSR1 (0.40) NPSR1TDP1RECQLXBP1MAPT
SCHEMBL21418111 0.80 PSMB5 (0.51) RECQLPSMB5
SCHEMBL25051421 0.80 RECQL (0.42) NPSR1ALDH1A1HRH3RECQLPSMB5
SCHEMBL25122213 0.79 RECQL (0.53) NPSR1ALDH1A1HRH3RECQLCA1
SCHEMBL22987342 0.79 RECQL (0.53) NPSR1ALDH1A1HRH3RECQLCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108727407-B Novel benzodiazepine derivatives 伊缪诺金公司 2022-01-28 CN disclosed
CN-105198908-B Novel benzodiazepine derivatives 伊缪诺金公司 2019-12-24 CN disclosed