Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25122213 | 1.00 | RECQL (0.53) | RECQLGAAPSMB5TSHRCAPN1 | |
| SCHEMBL21418111 | 0.88 | PSMB5 (0.51) | RECQLGAAPSMB5CAPN1 | |
| SCHEMBL25051421 | 0.88 | RECQL (0.42) | RECQLGAAPSMB5CAPN1ALDH1A1 | |
| SCHEMBL20436735 | 0.85 | RECQL (0.41) | RECQLGAAPSMB5CAPN1NPSR1 | |
| SCHEMBL17570956 | 0.85 | RECQL (0.39) | RECQLTSHRCAPN1NPSR1HRH3 | |
| SCHEMBL17616958 | 0.85 | RECQL (0.39) | RECQLTSHRCAPN1NPSR1HRH3 | |
| SCHEMBL18914007 | 0.82 | RECQL (0.39) | RECQLTSHRCAPN1ALDH1A1LMNA | |
| SCHEMBL22064571 | 0.82 | RECQL (0.48) | RECQLGAAPSMB5TSHRCAPN1 | |
| SCHEMBL22064576 | 0.81 | RECQL (0.56) | RECQLGAAPSMB5TSHRALDH1A1 | |
| SCHEMBL18411703 | 0.81 | RECQL (0.56) | RECQLGAAPSMB5TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |