Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069269 | 0.81 | MAOB (0.51) | MAOBAHRCYP1A2LMNAJAK2 | |
| SCHEMBL30987469 | 0.80 | MAOB (0.54) | MAOBLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL16519856 | 0.79 | MAOB (0.40) | MAOB | |
| SCHEMBL8138970 | 0.79 | KMT2A (0.40) | MAOBAHRCYP1A2MEN1MAPK1 | |
| SCHEMBL933856 | 0.79 | MAOA (0.51) | MAOB | |
| SCHEMBL164340 | 0.79 | MAOA (0.51) | MAOB | |
| SCHEMBL10261016 | 0.78 | MAOB (0.60) | MAOBL3MBTL1 | |
| SCHEMBL29168417 | 0.77 | ALDH1A1 (0.44) | MAOBLMNAALDH1A1 | |
| SCHEMBL24198614 | 0.77 | MAOA (0.53) | MAOB | |
| SCHEMBL11097338 | 0.77 | HSD17B10 (0.41) | MAOBAHRCYP1A2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615729-B | Method for selectively generating cis-olefin by deamination coupling of secondary carbon primary amine and aryl terminal alkyne | 中南大学 | 2020-09-15 | — | — | CN | disclosed |
| CN-110615729-A | Method for selectively generating cis-olefin by deamination coupling of secondary carbon primary amine and aryl terminal alkyne | 中南大学 | 2019-12-27 | — | — | CN | disclosed |