Quinoline

Quinoline

SCHEMBL28339254

CN1CC=Cc2ccccc21.c1ccc2ncccc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
POLB P06746 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
PDE10A Q9Y233 5/20 0.33
CYP3A4 P08684 1/20 0.33
CHKA P35790 1/20 0.33
HTR3A P46098 1/20 0.33
MEN1 O00255 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28168856 0.81 ALDH1A1 (0.42) ALDH1A1SLC6A2SLC6A4SLC6A3PDE10A
SCHEMBL29434173 0.80 P2RX4 (0.37) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4
SCHEMBL1198914 0.80 P2RX4 (0.37) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4
Quinoline SCHEMBL28157604 0.80 ALDH1A1 (0.44) ALDH1A1NPC1RAB9APOLBCYP3A4
Hydrochloric Acid SCHEMBL29035745 0.79 MEN1 (0.37) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4
Iodide SCHEMBL7101346 0.79 P2RX4 (0.36) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4
Iodide SCHEMBL27879086 0.79 P2RX4 (0.36) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4
Iodide SCHEMBL30253496 0.79 P2RX4 (0.36) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4
Quinoline SCHEMBL27519619 0.78 ALDH1A1 (0.61) ALDH1A1NPC1RAB9APOLBSLC6A2
Iodide SCHEMBL27895829 0.77 MAPT (0.36) ALDH1A1SLC6A2SLC6A4SLC6A3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110546001-B Laminated body 株式会社大赛璐 2022-05-03 CN disclosed
CN-113165015-A Weather-resistant hard coating composition for glass-substitute substrate, cured product, and laminate 株式会社大赛璐 2021-07-23 CN disclosed
CN-113165014-A Weather-resistant hard coating composition for metal, cured product, and coated metal substrate 株式会社大赛璐 2021-07-23 CN disclosed
CN-112135731-A Laminated film and foldable device 株式会社大赛璐 2020-12-25 CN disclosed
CN-111328378-A Plastic lens 株式会社大赛璐 2020-06-23 CN disclosed
CN-111095038-A Plastic lens 株式会社大赛璐 2020-05-01 CN disclosed
CN-110650987-A Composition for forming insulating film, and semiconductor device provided with insulating film 株式会社大赛璐 2020-01-03 CN disclosed
CN-110621494-A Hard coat film with suppressed curling and process for producing the same 株式会社大赛璐 2019-12-27 CN disclosed
CN-110621723-A Polyorganosilsesquioxane, transfer film, in-mold molded article, and hard coat film 株式会社大赛璐 2019-12-27 CN disclosed