SCHEMBL28339353

SCHEMBL28339353

Cc1cc(C)c(C(=O)P(C(=O)c2c(C)cc(C)cc2C)c2ccccc2)c(C)c1.Cc1cc(C)c([C]=O)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.33
KMT2A Q03164 5/20 0.32
MEN1 O00255 4/20 0.32
METAP2 P50579 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
KDM4E B2RXH2 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MCOLN3 Q8TDD5 1/20 0.31
CRHR1 P34998 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
RAB9A P51151 1/20 0.30
MAPT P10636 1/20 0.30
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
NFE2L2 Q16236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132877 0.89 LMNA (0.38) LMNAKMT2AMEN1METAP2HPGD
Water SCHEMBL25294008 0.88 LMNA (0.37) LMNAKMT2AMEN1METAP2HPGD
Lithium SCHEMBL30307087 0.88 LMNA (0.37) LMNAKMT2AMEN1METAP2HPGD
SCHEMBL26654506 0.88 LMNA (0.37) LMNAKMT2AMEN1METAP2HPGD
Hydrochloric Acid SCHEMBL28731761 0.88 LMNA (0.37) LMNAKMT2AMEN1METAP2HPGD
SCHEMBL15159273 0.84 L3MBTL1 (0.36) LMNAKMT2AMEN1METAP2HPGD
Propane SCHEMBL28243452 0.84 MEN1 (0.40) LMNAKMT2AMEN1METAP2ALDH1A1
SCHEMBL27984499 0.83 LMNA (0.36) LMNAKMT2AMEN1METAP2ALDH1A1
SCHEMBL27034025 0.81 HPGD (0.36) LMNAKMT2AMEN1METAP2HPGD
SCHEMBL2568219 0.77 KMT2A (0.38) LMNAKMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461962-A Photocurable hardcoat compositions, methods, and articles derived therefrom BASF SE 2019-11-15 CN disclosed