Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.86 |
| ▸ | MEN1 | O00255 | 4/20 | 0.86 |
| ▸ | RAB9A | P51151 | 3/20 | 0.86 |
| ▸ | NPC1 | O15118 | 2/20 | 0.86 |
| ▸ | POLB | P06746 | 1/20 | 0.86 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738509 | 1.00 | KMT2A (0.86) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28339464 | 1.00 | KMT2A (0.86) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28341788 | 0.89 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28341787 | 0.89 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL30738392 | 0.87 | RAB9A (0.65) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28339475 | 0.87 | RAB9A (0.65) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28339476 | 0.87 | RAB9A (0.65) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28339470 | 0.80 | KDM4E (0.62) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL28339471 | 0.80 | KDM4E (0.62) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL30584127 | 0.79 | MEN1 (0.67) | KMT2AMEN1RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483432-A | A kind of acrylic compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV FUDAN | 2019-11-22 | — | — | CN | disclosed |