Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | FOS | P01100 | 1/20 | 0.51 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738392 | 1.00 | RAB9A (0.65) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL28339475 | 1.00 | RAB9A (0.65) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL28339464 | 0.87 | KMT2A (0.86) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL28339462 | 0.87 | KMT2A (0.86) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL30738509 | 0.87 | KMT2A (0.86) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL28341869 | 0.85 | GPR183 (0.62) | RAB9ANPC1TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL28341866 | 0.85 | GPR183 (0.62) | RAB9ANPC1TRPV1ALDH1A1L3MBTL1 | |
| SCHEMBL11467113 | 0.84 | ACHE (0.57) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL11467112 | 0.84 | ACHE (0.57) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL3115230 | 0.82 | KMT2A (0.64) | RAB9AMEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483432-A | A kind of acrylic compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV FUDAN | 2019-11-22 | — | — | CN | disclosed |