Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Metacresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metacresol SCHEMBL1034095 | 1.00 | ACHE (0.81) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL15466197 | 0.93 | ACHE (0.77) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL6234380 | 0.93 | ACHE (0.94) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL29352064 | 0.90 | — | — | |
| Metacresol SCHEMBL10736 | 0.90 | — | — | |
| Metacresol SCHEMBL2314567 | 0.90 | ACHE (1.00) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL11437600 | 0.90 | ACHE (1.00) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL9774388 | 0.90 | ACHE (1.00) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL8883659 | 0.88 | ACHE (0.77) | ACHECYP1A2CYP2C19CA12CA2 | |
| Metacresol SCHEMBL11749131 | 0.88 | ACHE (0.85) | ACHECYP1A2CYP2C19CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120153028-A | Thermoplastic resin composition, method for preparing the same, and molded article comprising the same | 株式会社LG化学 | 2025-06-13 | — | — | CN | disclosed |
| CN-116179614-A | Preparation method and application of O-cymene-5-ol for cosmetics | 王叔和生物医药(武汉)有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-110662783-B | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2022-06-28 | — | — | CN | disclosed |
| CN-110621719-B | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2022-06-24 | — | — | CN | disclosed |
| CN-110612318-B | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2022-06-24 | — | — | CN | disclosed |
| CN-108368250-B | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2020-12-04 | — | — | CN | disclosed |
| CN-108473669-B | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2020-10-27 | — | — | CN | disclosed |
| CN-108368251-B | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2020-10-09 | — | — | CN | disclosed |
| CN-108046998-B | Preparation method of 3-methyl-4-isopropyl phenol | 武汉桀升生物科技有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-110662783-A | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2020-01-07 | — | — | CN | disclosed |
| CN-110621719-A | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2019-12-27 | — | — | CN | disclosed |
| CN-110621720-A | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2019-12-27 | — | — | CN | disclosed |
| CN-110612318-A | Aromatic polycarbonate oligomer solid | 本州化学工业株式会社 | 2019-12-24 | — | — | CN | disclosed |