Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31321628 | 0.83 | ALOX15 (0.52) | ALOX15TOP2ATSHRAKR1C3HSD17B10 | |
| SCHEMBL31321690 | 0.82 | ALOX15 (0.62) | ALOX15TOP2AHPGDAKR1C3KMT2A | |
| SCHEMBL15557536 | 0.81 | ALOX15 (0.57) | ALOX15TOP2AAKR1C3CYSLTR2CYSLTR1 | |
| SCHEMBL28339382 | 0.81 | KDM4E (0.49) | ALOX15TOP2AHPGDAKR1C3HSD17B10 | |
| SCHEMBL27614322 | 0.80 | KMT2A (0.52) | ALOX15TSHRHPGDLMNAKMT2A | |
| SCHEMBL15558179 | 0.80 | ALOX15 (0.63) | ALOX15TOP2AAKR1C3CYSLTR2CYSLTR1 | |
| SCHEMBL16672664 | 0.79 | L3MBTL1 (0.56) | ALOX15TOP2AAKR1C3LMNAKMT2A | |
| Acetic Acid SCHEMBL10998868 | 0.79 | TSHR (0.53) | TSHRHPGDHSD17B10LMNAKMT2A | |
| SCHEMBL15558909 | 0.79 | ALOX15 (0.62) | ALOX15TOP2AAKR1C3CYSLTR2CYSLTR1 | |
| Rubidium SCHEMBL38664118 | 0.79 | ALOX15 (0.48) | ALOX15TSHRHPGDCYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110621671-A | Benzofuran and benzothiophene derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-27 | — | — | CN | disclosed |