Pyrrole

Pyrrole

SCHEMBL28339735

O=c1cccc[nH]1.c1cc[nH]c1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FKBP5 Q13451 1/20 0.84
NOTUM Q6P988 2/20 0.41
ABL1 P00519 2/20 0.37
RIN1 Q13671 2/20 0.37
NSD2 O96028 1/20 0.37
PPARG P37231 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
DAO P14920 2/20 0.36
AURKA O14965 1/20 0.36
AURKB Q96GD4 1/20 0.36
INCENP Q9NQS7 1/20 0.36
PARP1 P09874 1/20 0.33
CRBN Q96SW2 1/20 0.33
MCL1 Q07820 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
ALDH1A1 P00352 2/20 0.32
ALOX5 P09917 1/20 0.31
TP53 P04637 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrole SCHEMBL15283506 0.97 FKBP5 (0.80) FKBP5NOTUMABL1RIN1NSD2
SCHEMBL27324502 0.92 FKBP5 (1.00) FKBP5NOTUMABL1RIN1NSD2
SCHEMBL9596 0.92
SCHEMBL1149107 0.89
SCHEMBL9813332 0.89
SCHEMBL25414048 0.89
SCHEMBL8004964 0.89
Methane SCHEMBL22588025 0.89
SCHEMBL98973 0.89
Potassium SCHEMBL31456747 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143098-A Compound with anti-inflammatory effect in root of Arnafion, and preparation and application thereof 中国科学院新疆理化技术研究所 2023-12-01 CN disclosed
CN-110526867-A A method of efficiently preparing blonanserin intermediate HUNAN XIANGZHONG PHARMACEUTICAL CO LTD 2019-12-03 CN disclosed