Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415560 | 0.89 | MAPT (0.51) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL9641181 | 0.85 | CYP3A4 (0.49) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL30977634 | 0.84 | CYP3A4 (0.48) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL18415496 | 0.84 | CYP3A4 (0.48) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL18415449 | 0.84 | CYP3A4 (0.48) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL31465685 | 0.84 | CYP3A4 (0.48) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL6431425 | 0.82 | ALDH1A1 (0.46) | CYP3A4TSHRALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7959792 | 0.79 | MAPT (0.50) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL31465669 | 0.78 | CYP3A4 (0.46) | CYP3A4TP53KDM4EMAPTALOX15 | |
| SCHEMBL7959789 | 0.78 | CYP3A4 (0.49) | CYP3A4TP53KDM4EMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561259-A | Preparation method of nitrogen-containing polycyclic condensed ring compound, intermediate and application thereof | 北京志健金瑞生物医药科技有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117342964-A | Synthesis method of N, N' -bis (2, 4, 6-trimethoxyphenyl) oxamide | 济南国鼎医药科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117024354-B | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117024354-A | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116903472-A | Synthesis method of 2,3,5, 6-tetramethyl p-phenylenediamine | 东营新阳光材料科技有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-115594678-A | Preparation method of nitrogen-containing polycyclic fused ring compound, intermediate and application thereof | 北京志健金瑞生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-110590692-A | 6H-1, 3-oxazoline-6-ketone compound and application thereof in drugs for treating attention deficit hyperactivity disorder | 张振亭 | 2019-12-20 | — | — | CN | claimed |
| CN-117561259-A | Preparation method of nitrogen-containing polycyclic condensed ring compound, intermediate and application thereof | 北京志健金瑞生物医药科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117342964-A | Synthesis method of N, N' -bis (2, 4, 6-trimethoxyphenyl) oxamide | 济南国鼎医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117342964-A | Synthesis method of N, N' -bis (2, 4, 6-trimethoxyphenyl) oxamide | 济南国鼎医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117342964-A | Synthesis method of N, N' -bis (2, 4, 6-trimethoxyphenyl) oxamide | 济南国鼎医药科技有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-117327075-A | Bicyclic compounds as allosteric SHP2 inhibitors | 锐新医药公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117024354-B | Preparation method of Rui Mi Buti Ni | 天津凯莱英制药有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-116783160-A | Libraries of compounds | 中外制药株式会社 | 2023-09-19 | — | — | CN | disclosed |
| CN-110446709-B | Bicyclic compounds as allosteric SHP2 inhibitors | 锐新医药公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116670144-A | Tricyclic compounds and uses thereof | 南京再明医药有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115594678-A | Preparation method of nitrogen-containing polycyclic fused ring compound, intermediate and application thereof | 北京志健金瑞生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-113717201-B | (+/-) -Marinopyrole A derivative and preparation method and application thereof | 植恩生物技术股份有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113717201-A | (+/-) -Marinopyrole A derivative and preparation method and application thereof | 植恩生物技术股份有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-110590692-A | 6H-1, 3-oxazoline-6-ketone compound and application thereof in drugs for treating attention deficit hyperactivity disorder | 张振亭 | 2019-12-20 | — | — | CN | disclosed |