Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342854 | 0.88 | EP300 (0.43) | EP300PPARGPPARAHCAR2PTPN1 | |
| SCHEMBL28340301 | 0.87 | FAAH (0.49) | EP300MAPTBLMHSD17B10USP2 | |
| SCHEMBL28340316 | 0.87 | POLB (0.39) | EP300PPARGPPARAPOLB | |
| SCHEMBL28881050 | 0.85 | CNR1 (0.51) | MAPTFAAHKMT2A | |
| SCHEMBL28340384 | 0.84 | HRH3 (0.40) | EP300PPARGPPARAHCAR2PTPN1 | |
| SCHEMBL28340556 | 0.81 | POLB (0.35) | EP300PPARGPPARASOAT2SOAT1 | |
| SCHEMBL28342840 | 0.80 | ZDHHC2 (0.52) | SOAT2SOAT1LMNAPOLBFAAH | |
| SCHEMBL28810987 | 0.79 | ATM (0.42) | EP300HCAR2MAPTPOLBNPSR1 | |
| SCHEMBL28342912 | 0.79 | ALDH1A1 (0.46) | EP300PPARGPPARAHCAR2PTPN1 | |
| SCHEMBL23795446 | 0.79 | EP300 (0.50) | EP300PPARGPPARAHCAR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642737-B | Preparation method of amide-substituted (E, E) -configuration branched conjugated diene derivative | 杭州师范大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-110642737-A | Amide-substituted (E, E) -configuration branched conjugated diene derivative and preparation method thereof | 杭州师范大学 | 2020-01-03 | — | — | CN | disclosed |