Biphenyl

Biphenyl

SCHEMBL28340467

NC(=O)NC=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
BCAT2 O15382 1/20 0.41
IKBKB O14920 2/20 0.40
DHODH Q02127 1/20 0.40
MAPT P10636 4/20 0.39
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
TP53 P04637 1/20 0.39
PTPN1 P18031 1/20 0.39
PTPN11 Q06124 1/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
PARP1 P09874 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27335460 0.86 TSHR (0.35) LMNABCAT2MAPTGAAGFER
Benzenethiol SCHEMBL28242637 0.83 MAPT (0.37) LMNAHDAC2HDAC1HDAC6BCAT2
Catechol SCHEMBL27477807 0.83 KDM4E (0.45) LMNANPC1RAB9AMAPTGAA
Biphenyl SCHEMBL28574042 0.79 NPC1 (0.42) LMNAHDAC2NPC1RAB9ACTDSP1
SCHEMBL20457 0.78
SCHEMBL28045225 0.77 MAPT (0.43) LMNANPC1RAB9AMAPTGAA
Biphenyl SCHEMBL11033740 0.77 TSHR (0.53) LMNANPC1RAB9ACTDSP1BCAT2
Biphenyl SCHEMBL9421865 0.77 LMNA (0.48) LMNANPC1RAB9ACTDSP1BCAT2
Biphenyl SCHEMBL28574043 0.77 LMNA (0.48) LMNABCAT2IKBKBDHODHMAPT
P-Xylene SCHEMBL28228344 0.76 KIF11 (0.48) LMNAHDAC1HDAC6GAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461939-A Epoxy resin composition for sealing and electronic component device HITACHI CHEMICAL CO LTD 2019-11-15 CN disclosed