SCHEMBL28340752

SCHEMBL28340752

CCC(=O)OCC(=O)CCCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.51
HDAC1 Q13547 3/20 0.51
HDAC2 Q92769 3/20 0.51
HDAC8 Q9BY41 3/20 0.51
HDAC6 Q9UBN7 3/20 0.51
HDAC5 Q9UQL6 3/20 0.51
HDAC4 P56524 2/20 0.51
HDAC7 Q8WUI4 2/20 0.51
HDAC10 Q969S8 2/20 0.51
HDAC11 Q96DB2 2/20 0.51
HDAC9 Q9UKV0 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MAPK1 P28482 1/20 0.51
ADRA1A P35348 1/20 0.51
SLC6A3 Q01959 1/20 0.51
ALOX5 P09917 1/20 0.50
TDP1 Q9NUW8 3/20 0.49
NPC1 O15118 1/20 0.47
CASP3 P42574 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28343655 0.84 HDAC1 (0.55) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL3642535 0.81 HDAC1 (0.64) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL873128 0.80 LMNA (0.64) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL5310166 0.80 LMNA (0.64) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL544942 0.80 HDAC1 (0.58) HDAC3HDAC1HDAC2HDAC8HDAC6
Ammonia Solution, Strong SCHEMBL6014478 0.80 HDAC1 (0.62) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL28343245 0.79 TDP1 (0.57) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL7044306 0.79 HCAR2 (0.55) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL28343440 0.79 HDAC1 (0.49) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL16672854 0.79 TDP1 (0.58) SMN1; SMN2TDP1NPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110668937-B Method for preparing ester compound from amide 徐州医科大学 2022-04-19 CN disclosed
CN-110668937-A Method for preparing ester compound from amide 徐州医科大学 2020-01-10 CN disclosed