SCHEMBL873128

SCHEMBL873128

CCC(=O)OCCCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.64
TDP1 Q9NUW8 1/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
ALDH1A1 P00352 2/20 0.59
CTDSP1 Q9GZU7 2/20 0.58
KDM4E B2RXH2 1/20 0.58
APOBEC3A P31941 2/20 0.57
APOBEC3G Q9HC16 2/20 0.57
MAPT P10636 1/20 0.57
NPC1 O15118 1/20 0.57
RECQL P46063 1/20 0.57
RAB9A P51151 1/20 0.57
MEN1 O00255 1/20 0.55
POLB P06746 1/20 0.55
KMT2A Q03164 1/20 0.55
CYP2D6 P10635 1/20 0.55
FFAR1 O14842 1/20 0.53
HTT P42858 1/20 0.51
CTSK P43235 1/20 0.50
MMP1 P03956 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5310166 1.00 LMNA (0.64) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
SCHEMBL16672854 0.95 TDP1 (0.58) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
SCHEMBL9180923 0.93 HTT (0.56) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
SCHEMBL6989966 0.93 HTT (0.56) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
Acrylic Acid SCHEMBL28013212 0.91 LMNA (0.54) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
Phenethyl Propionate SCHEMBL114088 0.89 TDP1 (0.63) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
SCHEMBL8817029 0.86 TDP1 (0.66) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
Phenethyl Propionate SCHEMBL28805171 0.86 TDP1 (0.59) LMNATDP1SMN1; SMN2ALDH1A1CTDSP1
Phenethyl Propionate SCHEMBL4653082 0.86 TDP1 (0.59) LMNATDP1SMN1; SMN2ALDH1A1KDM4E
Phenethyl Propionate SCHEMBL27857110 0.86 TDP1 (0.59) LMNATDP1SMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119816291-A Agent for promoting formation of horny layer 株式会社资生堂 2025-04-11 CN claimed
WO-2024062675-A1 STRATUM CORNEUM FORMATION PROMOTER 株式会社 資生堂 2024-03-28 WO claimed
CN-110300791-A Quantum dot dispersion, self-luminous photosensitive resin composition, color filter, and image display device 东友精细化工有限公司 2019-10-01 CN claimed
US-9050295-B2 Composition for treatment of tuberculosis ETH ZURICH (CH) 2015-06-09 US claimed
EP-2234643-B1 COMPOSITION FOR TREATMENT OF TUBERCULOSIS ETH ZUERICH (CH) 2013-01-09 EP claimed
US-20110053880-A1 COMPOSITION FOR TREATMENT OF TUBERCULOSIS ETH ZURICH (CH) 2011-03-03 US claimed
EP-2234643-A2 COMPOSITION FOR TREATMENT OF TUBERCULOSIS ETH Zurich (CH) 2010-10-06 EP claimed
EP-1967080-B1 Non-aldehyde cinnamon flavor and delivery systems therefor CADBURY ADAMS USA LLC (US) 2010-06-02 EP claimed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO claimed
WO-2009080432-A2 COMPOSITION FOR TREATMENT OF TUBERCULOSIS ETH ZURICH (CH) 2009-07-02 WO claimed
EP-1967080-A1 Non-aldehyde cinnamon flavor and delivery systems therefor Cadbury Adams USA LLC (US) 2008-09-10 EP claimed
US-20080213440-A1 Non-Aldehyde Cinnamon Flavor and Delivery Systems Therefor CADBURY ADAMS USA LLC (US) 2008-09-04 US claimed
CN-119816291-A Agent for promoting formation of horny layer 株式会社资生堂 2025-04-11 CN disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
WO-2024062675-A1 STRATUM CORNEUM FORMATION PROMOTER 株式会社 資生堂 2024-03-28 WO disclosed
CN-1404474-A Arylpiperazines and arylpiperidines and their use as metalloproteinase inhibitors ASTRAZENECA AB (SE) 2003-03-19 CN disclosed
EP-0044541-B1 AMINOCARBOXYLIC ACIDS, AMINO ALCOHOLS, OR THE DERIVATIVES THEREOF, PROCESSES FOR PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION, CONTAINING AT LEAST ONE OF THESE COMPOUNDS TEIJIN LIMITED (JP) 1983-09-21 EP disclosed
US-4402975-A ANTIULCER AGENTS TEIJIN LIMITED (JP) 1983-09-06 US disclosed
EP-0044541-A1 Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical composition, containing at least one of these compounds TEIJIN LIMITED (JP) 1982-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 LMNA 4834/4885TDP1 2650/4885SMN1; SMN2 1778/4885
US-20110053880-A1 COMPOSITION FOR TREATMENT OF TUBERCULOSIS NCOR1, NCOR2, ESRRA LMNA 3188/4885TDP1 3153/4885SMN1; SMN2 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.