Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21774466 | 1.00 | LMNA (0.44) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL21774471 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1GAAUSP2 | |
| SCHEMBL20488971 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1GAAUSP2 | |
| SCHEMBL8755755 | 0.79 | RNPEP (0.48) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL5179354 | 0.79 | RNPEP (0.48) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL149342 | 0.79 | RNPEP (0.48) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL3869335 | 0.79 | LMNA (0.51) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL3869337 | 0.79 | LMNA (0.51) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL14404929 | 0.79 | LMNA (0.51) | LMNARNPEPPKMALDH1A1NPSR1 | |
| SCHEMBL5179360 | 0.79 | RNPEP (0.48) | LMNARNPEPPKMALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603252-A | Aryl, heteroaryl and heterocyclic pharmaceutical compounds for the treatment of medical disorders | 艾其林医药公司 | 2019-12-20 | — | — | CN | disclosed |