SCHEMBL28340765

SCHEMBL28340765

O=C(OC(=O)C(Cl)(Cl)Cl)C(F)(F)F.[NaH]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570453 0.97 ALDH1A1 (0.33) ALDH1A1TP53TSHR
SCHEMBL28329124 0.86 ALDH1A1 (0.41) ALDH1A1TP53TSHR
SCHEMBL28821507 0.86 ALDH1A1 (0.41) ALDH1A1TP53TSHR
SCHEMBL28456697 0.86 CA2 (0.33)
Chloromethane SCHEMBL28080031 0.83 CA2 (0.32) ALDH1A1TSHR
SCHEMBL28823736 0.83 CA2 (0.32)
SCHEMBL27623481 0.83 CA2 (0.35)
SCHEMBL150679 0.83 ALDH1A1 (0.44) ALDH1A1TP53TSHR
SCHEMBL52 0.83 CA2 (0.35)
SCHEMBL27674141 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111448194-A 3-amino- [1,2, 4] -triazole derivatives and their use for controlling undesired vegetation 拜耳作物科学股份公司 2020-07-24 CN disclosed
CN-111031799-A Substituted isothiazolopyridinones, method for the production thereof and use thereof as herbicides and/or plant growth regulators 拜耳作物科学股份公司 2020-04-17 CN disclosed
CN-110650628-A Trisubstituted silylheteroaryloxyquinolines and analogs thereof 拜耳公司 2020-01-03 CN disclosed
CN-110582484-A Trisubstituted silylmethylphenoxyquinolines and analogs thereof 拜耳公司 2019-12-17 CN disclosed