Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | F2 | P00734 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880300 | 0.86 | TSHR (0.81) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL16026455 | 0.83 | MAPT (0.82) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL31488466 | 0.83 | TSHR (0.76) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL5050992 | 0.83 | TSHR (0.76) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL28880361 | 0.82 | KDM4E (1.00) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL29506259 | 0.81 | CNR1 (0.78) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL30410560 | 0.81 | TSHR (0.72) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL18751343 | 0.80 | TSHR (0.71) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL11887626 | 0.80 | TSHR (0.71) | TSHRGAAKDM4EPOLBMAPT | |
| SCHEMBL14428441 | 0.80 | FPR2 (0.88) | TSHRPOLBMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777597-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2020-10-16 | — | — | CN | claimed |
| CN-110627774-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2019-12-31 | — | — | CN | claimed |
| CN-111777597-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2020-10-16 | — | — | CN | disclosed |
| CN-110627774-A | Anti-hepatic fibrosis compound, preparation method and application | 江西省医学科学院 | 2019-12-31 | — | — | CN | disclosed |