SCHEMBL5050992

SCHEMBL5050992

CC(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O

nearest known ligand 0.76

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.76
KDM4E B2RXH2 1/20 0.76
MAPT P10636 1/20 0.74
GAA P10253 3/20 0.73
LMNA P02545 1/20 0.73
POLB P06746 2/20 0.69
KMT2A Q03164 2/20 0.69
MEN1 O00255 1/20 0.69
FPR2 P25090 2/20 0.67
TP53 P04637 1/20 0.67
HSD17B10 Q99714 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
L3MBTL1 Q9Y468 3/20 0.66
ALDH1A1 P00352 2/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28880300 0.91 TSHR (0.81) TSHRKDM4EMAPTGAALMNA
SCHEMBL23400077 0.88 KDM4E (0.63) TSHRKDM4EMAPTGAALMNA
SCHEMBL23403469 0.88 TSHR (0.58) TSHRKDM4EMAPTGAALMNA
SCHEMBL28880361 0.87 KDM4E (1.00) TSHRKDM4EMAPTGAALMNA
SCHEMBL28492314 0.86 TSHR (0.69) TSHRKDM4EMAPTGAALMNA
SCHEMBL30410560 0.85 TSHR (0.72) TSHRKDM4EMAPTGAALMNA
SCHEMBL28496843 0.85 KDM4E (0.67) TSHRKDM4EMAPTGAALMNA
SCHEMBL14428441 0.84 FPR2 (0.88) TSHRMAPTPOLBKMT2AMEN1
SCHEMBL28340952 0.83 TSHR (0.82) TSHRKDM4EMAPTGAALMNA
SCHEMBL8651089 0.83 KDM4E (0.68) TSHRKDM4EMAPTGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113200916-A Antipyrine functional monomer, preparation method thereof and organophosphorus pesticide molecularly imprinted polymer prepared based on antipyrine functional monomer 天津科技大学 2021-08-03 CN claimed
US-20250376689-A1 OLIGONUCLEOTIDES HAVING 6-THIO-2'-DEOXYGUANOSINE RESIDUES AND USES THEREOF HOPE CITY (US) 2025-12-11 US disclosed
CN-118829450-A Eptification derivative-antibody conjugate and medical application thereof 甘李药业股份有限公司 2024-10-22 CN disclosed
CN-116672759-A Neodymium-silicon co-doped TiO 2 Application of nano material, processing method of animal-derived food sample and application of animal-derived food sample 中国检验认证集团湖南有限公司 2023-09-01 CN disclosed
CN-114315723-B Analgin residual marker hapten and artificial antigen as well as preparation methods and applications thereof 中国农业大学 2023-08-08 CN disclosed
CN-116514718-A Hybridoma cell strain, analgin residue marker 4-methylamino antipyrine monoclonal antibody secreted by hybridoma cell strain and application of analgin residue marker 河南农业大学 2023-08-01 CN disclosed
CN-113676903-B Slice authentication authorization management method, device and system 华为技术有限公司 2023-03-10 CN disclosed
CN-114480382-A RNAi agents and compositions for inhibiting SURF4 gene expression 北京大学 2022-05-13 CN disclosed
CN-114315723-A Analgin residual marker hapten and artificial antigen as well as preparation methods and application thereof 中国农业大学 2022-04-12 CN disclosed
CN-113200916-A Antipyrine functional monomer, preparation method thereof and organophosphorus pesticide molecularly imprinted polymer prepared based on antipyrine functional monomer 天津科技大学 2021-08-03 CN disclosed
US-20020132935-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-09-19 US disclosed
US-20020071955-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-06-13 US disclosed
US-20020040112-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-04-04 US disclosed
US-20020037973-A1 Modified aminoplast crosslinkers and powder coating compositions containing such crosslinkers PPG INDUSTRIES OHIO, INC. 2002-03-28 US disclosed
EP-1150660-A1 PHARMACEUTICAL EFFERVESCENT FORMULATION CONTAINING METAMIZOL HEXAL AG (DE) 2001-11-07 EP disclosed
WO-2000066088-A1 CONTROLLED RELEASE PHARMACEUTICAL PREPARATION CONTAINING METAMIZOLE HEXAL AG (DE) 2000-11-09 WO disclosed
WO-2000047189-A1 PHARMACEUTICAL EFFERVESCENT FORMULATION CONTAINING METAMIZOL HEXAL AG (DE) 2000-08-17 WO disclosed
US-5760216-A REACTING DRUG SAMPLE WITH SYNTHETIC METALLOPORPHYRIN, OXIDIZING AGENT, SOLVENT TO FORM OXIDATION PRODUCT ABBOTT LABORATORIES (US) 1998-06-02 US disclosed
EP-0781261-A2 USE OF SYNTHETIC METALLOPORPHYRINS FOR PREPARATION AND PREDICTION OF DRUG METABOLITES Abbott Laboratories (US) 1997-07-02 EP disclosed
WO-1996008455-A2 USE OF SYNTHETIC METALLOPORPHYRINS FOR PREPARATION AND PREDICTION OF DRUG METABOLITES ABBOTT LABORATORIES (US) 1996-03-21 WO disclosed