Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263539 | 0.90 | KDM4E (0.56) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL1912705 | 0.88 | KDM4E (0.62) | JAK2JAK1STSKDM4EPKM | |
| SCHEMBL23120360 | 0.87 | NAMPT (0.46) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL5327343 | 0.86 | GPR119 (0.48) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL23120587 | 0.86 | NAMPT (0.47) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL17736150 | 0.86 | NAMPT (0.56) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL1573158 | 0.85 | JAK2 (0.46) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL1573262 | 0.85 | JAK2 (0.46) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL18497493 | 0.85 | NAMPT (0.51) | NAMPTJAK2JAK1STSKDM4E | |
| SCHEMBL21381846 | 0.84 | MAPT (0.47) | NAMPTKDM4EPKMRORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110662541-A | Polycyclic amines as opioid receptor modulators | 王晓冬 | 2020-01-07 | — | — | CN | disclosed |