Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | STS | P08842 | 1/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | JAK1 | P23458 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | YAP1 | P46937 | 2/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263539 | 0.94 | KDM4E (0.56) | KDM4EPKMSTSGPR119JAK2 | |
| SCHEMBL13913655 | 0.92 | KDM4E (0.60) | KDM4EPKMSTSGPR119JAK2 | |
| SCHEMBL3358948 | 0.91 | KDM4E (0.59) | KDM4EPKMSTSGPR119JAK2 | |
| SCHEMBL1532820 | 0.89 | KDM4E (0.55) | KDM4EPKMSTSGPR119JAK2 | |
| SCHEMBL12736015 | 0.88 | KDM4E (0.56) | KDM4EPKMSTSGPR119FAAH | |
| SCHEMBL13282013 | 0.88 | MAOB (0.53) | KDM4EPKMGPR119TGFBR1MAOB | |
| SCHEMBL20015389 | 0.88 | GPR119 (0.60) | KDM4EPKMGPR119SMN1; SMN2MAOB | |
| SCHEMBL30824890 | 0.88 | GPR119 (0.58) | KDM4EPKMSTSGPR119FAAH | |
| SCHEMBL3923737 | 0.88 | KDM4E (0.64) | KDM4EPKMSTSGPR119FAAH | |
| SCHEMBL28341502 | 0.88 | NAMPT (0.54) | KDM4EPKMSTSGPR119JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| WO-2018055096-A1 | DISUBTITUTED AZETIDINES, PYRROLIDINES, PIPERIDINES AND AZEPANES AS INHIBITORS OF MONOAMINE OXIDASE B FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERSITY OF LJUBLJANA (SI) | 2018-03-29 | — | — | WO | disclosed |
| US-20120010135-A1 | SPIRO DERIVATIVES FOR THE MODULATION OF STEAROYL-COA DESATURASE | XENON PHARMACEUTICALS INC. (CA) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010135-A1 | SPIRO DERIVATIVES FOR THE MODULATION OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | KDM4E 1529/4885PKM 2363/4885STS 94/4885 |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | VIM, ACE, ACE2 | KDM4E 2900/4885PKM 3044/4885STS 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.