SCHEMBL28341872

SCHEMBL28341872

CC(C)Cc1ccc2ccnc(Cl)c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.40
MAPK1 P28482 2/20 0.40
PARG Q86W56 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
APEX1 P27695 1/20 0.40
PMP22 Q01453 1/20 0.40
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
PLAU P00749 1/20 0.36
ABL1 P00519 1/20 0.36
KDM4E B2RXH2 2/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
IKBKE Q14164 1/20 0.35
TBK1 Q9UHD2 1/20 0.35
ALOX5AP P20292 1/20 0.34
PNMT P11086 1/20 0.34
CYP2C19 P33261 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24146531 0.87 ROCK1 (0.41) CYP3A4MAPK1LMNAMAPTAPEX1
SCHEMBL6990828 0.80 CYP3A4 (0.44) CYP3A4MAPK1PARGLMNAMAPT
Hydrochloric Acid SCHEMBL6993550 0.78 CYP3A4 (0.43) CYP3A4MAPK1PARGLMNAMAPT
SCHEMBL6997520 0.78 PLAU (0.56) CYP3A4MAPK1PARGLMNAMAPT
SCHEMBL7214319 0.78 CYP3A4 (0.43) CYP3A4MAPK1PARGLMNAMAPT
SCHEMBL7390612 0.75 PLAU (0.43) CYP3A4MAPK1PARGLMNAMAPT
SCHEMBL13389172 0.75 KDM4E (0.37) GABRA1GABRB2PLAUABL1KDM4E
SCHEMBL26910255 0.75 LMNA (0.43) CYP3A4MAPK1PARGLMNAMAPT
SCHEMBL21405679 0.73 PARG (0.45) CYP3A4MAPK1PARGLMNAMAPT
SCHEMBL24146568 0.73 GABRA1 (0.37) GABRA1GABRB2ABL1SMN1; SMN2IKBKE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110627836-A Red phosphorescent compound and organic electroluminescent device using the same 浙江华显光电科技有限公司 2019-12-31 CN disclosed