Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | RXRA | P19793 | 4/20 | 0.44 |
| ▸ | RXRG | P48443 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984662 | 0.84 | RXRB (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2RXRB | |
| SCHEMBL28342439 | 0.83 | LMNA (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28342373 | 0.80 | CHRM1 (0.44) | — | |
| SCHEMBL28339934 | 0.80 | CHRM5 (0.48) | NPC1RAB9A | |
| SCHEMBL20809634 | 0.80 | PPARG (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2RXRB | |
| SCHEMBL6348602 | 0.79 | RXRB (0.50) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28342389 | 0.78 | CHRM5 (0.53) | NPC1RAB9AMAPT | |
| SCHEMBL28342443 | 0.78 | CHRM1 (0.50) | NPC1RAB9ALMNA | |
| SCHEMBL28813907 | 0.78 | RXRB (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3811959 | 0.77 | ALOX15 (0.55) | NPC1RAB9AALDH1A1RXRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612299-A | Pyrimidine derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2019-12-24 | — | — | CN | disclosed |