SCHEMBL28343157

SCHEMBL28343157

NC(CCC(N)c1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.53
GRM2 Q14416 2/20 0.53
GRM3 Q14832 2/20 0.53
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.52
XIAP P98170 1/20 0.52
SLC7A5 Q01650 1/20 0.52
LTA4H P09960 1/20 0.50
POLB P06746 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2781356 0.82 DPP4 (0.55)
SCHEMBL2784864 0.82 DPP4 (0.55)
SCHEMBL2781359 0.82 DPP4 (0.55)
Hydrochloric Acid SCHEMBL15372828 0.81 APAF1 (0.50) GRM2GRM3
SCHEMBL5325671 0.81 KIF11 (0.50) KIF11GRM2GRM3ALPIPKM
SCHEMBL7457032 0.79 GRM2 (0.55) GRM2GRM3
SCHEMBL7006798 0.78 ALPI (0.50) KIF11GRM2GRM3ALPIPKM
Aspartic Acid SCHEMBL17074056 0.78 GRM2 (0.47) KIF11GRM2GRM3ALPIPKM
SCHEMBL12682235 0.78 CYP1A2 (0.48) GRM2GRM3LTA4HPOLB
SCHEMBL372488 0.78 CYP1A2 (0.48) GRM2GRM3LTA4HPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621688-A Means and methods for treating bacterial infections 非营利性组织佛兰芒综合大学生物技术研究所 2019-12-27 CN disclosed