Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28343220 | 0.91 | MAOB (0.59) | MAOBMAOAPTGS2MEN1PPARG | |
| SCHEMBL28346645 | 0.88 | MAOB (0.60) | MAOBMAOAPTGS2LMNANT5E | |
| SCHEMBL28346042 | 0.78 | MAOB (0.52) | MAOBMAOAPTGS2MEN1PPARG | |
| SCHEMBL1658926 | 0.76 | NT5E (0.82) | MAOBNPC1RAB9ANT5EACHE | |
| SCHEMBL14133297 | 0.76 | ALDH1A1 (0.66) | MAOBMAOAPTGS2NPC1RAB9A | |
| SCHEMBL14133506 | 0.75 | MAOB (0.70) | MAOBMAOAPTGS2NPC1RAB9A | |
| SCHEMBL14133755 | 0.75 | MAOB (0.70) | MAOBMAOAPTGS2NPC1RAB9A | |
| SCHEMBL14133296 | 0.74 | MAPT (0.81) | MAOBMAOAPTGS2PKMMEN1 | |
| SCHEMBL20989157 | 0.74 | NPSR1 (0.58) | PTGS2LMNAPKMMEN1PPARG | |
| SCHEMBL8208092 | 0.74 | MAOB (0.72) | MAOBMAOAPTGS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |