Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346042 | 0.90 | MAOB (0.52) | MAOBPTGS2MAOAMEN1PPARG | |
| SCHEMBL28343226 | 0.88 | MAOB (0.64) | MAOBPTGS2MAOALMNAACHE | |
| SCHEMBL28343220 | 0.79 | MAOB (0.59) | MAOBPTGS2MAOAKDM4EMEN1 | |
| SCHEMBL20989157 | 0.77 | NPSR1 (0.58) | PTGS2LMNAPKMKDM4EMEN1 | |
| SCHEMBL14133297 | 0.75 | ALDH1A1 (0.66) | MAOBPTGS2MAOAPKMKDM4E | |
| SCHEMBL14133335 | 0.75 | ALDH1A1 (0.65) | MAOBPTGS2MAOAPKMKDM4E | |
| SCHEMBL1658926 | 0.73 | NT5E (0.82) | MAOBACHENT5E | |
| SCHEMBL14133506 | 0.72 | MAOB (0.70) | MAOBPTGS2MAOAKDM4EMEN1 | |
| SCHEMBL14133755 | 0.72 | MAOB (0.70) | MAOBPTGS2MAOAPKMKDM4E | |
| SCHEMBL3312460 | 0.72 | MAOB (0.78) | MAOBMAOAACHEPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | claimed |
| CN-107827820-B | Pyrazoline aminopeptidase N inhibitor and preparation method and application thereof | 山东大学 | 2020-01-07 | — | — | CN | disclosed |