Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060174 | 0.93 | PARP10 (0.65) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL5578147 | 0.91 | PARP10 (0.72) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL382507 | 0.91 | PARP10 (0.72) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL105134 | 0.89 | PARP10 (0.59) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL9663679 | 0.85 | PARP10 (0.81) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6196601 | 0.84 | PARP10 (0.54) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8205435 | 0.83 | PARP10 (0.78) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL725405 | 0.83 | PARP10 (0.77) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL16050040 | 0.81 | PARP10 (0.74) | PARP10KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL533394 | 0.80 | HSD17B10 (0.50) | PARP10KMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| CN-114751920-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114736219-B | Antitumor compounds | 法马马有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114736219-A | Antitumor compounds | 法马马有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | disclosed |
| CN-110621678-A | Antitumor compounds | 法马马有限公司 | 2019-12-27 | — | — | CN | disclosed |