SCHEMBL5578147

SCHEMBL5578147

O=C(Oc1ccc([C](c2ccccc2)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.72
KMT2A Q03164 10/20 0.64
MEN1 O00255 3/20 0.64
MAPT P10636 4/20 0.62
TDP1 Q9NUW8 2/20 0.62
ALDH1A1 P00352 2/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
PKM P14618 1/20 0.62
RAB9A P51151 1/20 0.59
ELANE P08246 1/20 0.55
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
TMPRSS15 P98073 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
HSD17B10 Q99714 1/20 0.53
CASP3 P42574 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
F2 P00734 1/20 0.52
LMNA P02545 1/20 0.52
NSD2 O96028 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382507 1.00 PARP10 (0.72) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL9663679 0.94 PARP10 (0.81) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL8205435 0.91 PARP10 (0.78) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL725405 0.91 PARP10 (0.77) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL28343302 0.91 PARP10 (0.62) PARP10KMT2AMEN1MAPTTDP1
Hydrochloric Acid SCHEMBL16050040 0.89 PARP10 (0.74) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL5676789 0.88 PARP10 (0.72) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL622771 0.88 PARP10 (0.72) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL10610456 0.88 PARP10 (0.72) PARP10KMT2AMEN1MAPTTDP1
SCHEMBL8206009 0.88 PARP10 (0.72) PARP10KMT2AMEN1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648220-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA, Jyoti (SE) 1995-04-19 EP claimed
CN-118355117-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-07-16 CN disclosed
CN-118139629-A Compositions and methods for editing MECP2 transcripts 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-118139977-A Double-stranded oligonucleotide compositions and methods relating thereto 波涛生命科学有限公司 2024-06-04 CN disclosed
CN-117965536-A Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2024-05-03 CN disclosed
CN-117794560-A Stapled peptides and methods thereof 弗格制药有限公司 2024-03-29 CN disclosed
CN-117412761-A Antibody drug conjugates for delivery of cytotoxic agents using MATE technology 拜奥海芬治疗学有限公司 2024-01-16 CN disclosed
CN-110023322-B Novel bicyclic nucleosides and oligomers prepared therefrom 伯尔尼大学 2023-10-27 CN disclosed
CN-116940679-A Oligomeric compounds for dystrophin rescue in DMD patients by skipping of exon-51 SQY治疗公司 2023-10-24 CN disclosed
CN-108135921-B Oligonucleotide compositions and methods thereof 波涛生命科学有限公司 2023-10-17 CN disclosed
US-20040043951-A1 Hydrogelation agents NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-03-04 US disclosed
CN-1134426-C Method for preparing substituted benzodihydropyran derivative ���ƻ�ѧ������˾ 2004-01-14 CN disclosed
CN-1116292-C Process for preparing benzodihydropyranol deriv. BASF AG (DE) 2003-07-30 CN disclosed
EP-1129207-A1 CATALYTIC ANTIBODIES AND METHOD FOR PRODUCING CHROMANES BY CYCLIZATION WITH SAID ANTIBODIES BASF AKTIENGESELLSCHAFT (DE) 2001-09-05 EP disclosed
CN-1264705-A Method for preparing substituted benzodihydropyran derivative BASF AG (DE) 2000-08-30 CN disclosed
WO-2000028330-A1 METHOD FOR SELECTING CATALYTIC ANTIBODIES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
WO-2000028063-A1 CATALYTIC ANTIBODIES AND METHOD FOR PRODUCING CHROMANES BY CYCLIZATION WITH SAID ANTIBODIES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
WO-2000027884-A1 ANTIBODIES, MINI-ANTIBODIES OR ANTIBODY FRAGMENTS BINDING TO VITAMIN E AND THE USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
CN-1249306-A Process for preparing benzodihydropyranol deriv. BASF AG (DE) 2000-04-05 CN disclosed
CN-1111249-A TTTr as protective group in nucleotide synthesis CIBA GEIGY AG (CH) 1995-11-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043951-A1 Hydrogelation agents H1-2, GNA11, H1-0 PARP10 406/4885KMT2A 1901/4885MEN1 3848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.