Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 16/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 9/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341051 | 0.84 | CSF1R (0.46) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL28343616 | 0.84 | CSF1R (0.47) | CSF1RPDGFRAPDGFRBFLT3KIT | |
| SCHEMBL16028492 | 0.81 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL28463024 | 0.81 | CSF1R (0.61) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL28343787 | 0.80 | CSF1R (0.63) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL16028450 | 0.79 | CSF1R (0.85) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL16028595 | 0.78 | CSF1R (0.54) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL28343606 | 0.78 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL28881229 | 0.78 | TGFBR1 (0.41) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 | |
| SCHEMBL28341052 | 0.78 | CSF1R (0.66) | CSF1RPDGFRAPDGFRBCYP2C9FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228620-B | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2020-09-04 | — | — | CN | claimed |
| CN-112047927-A | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-105228620-B | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-110563700-A | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2019-12-13 | — | — | CN | disclosed |