Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 16/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 9/20 | 0.61 |
| ▸ | FLT3 | P36888 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341052 | 0.83 | CSF1R (0.66) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28467585 | 0.83 | CSF1R (0.45) | CSF1RPDGFRAPDGFRBFLT3KIT | |
| SCHEMBL28341051 | 0.82 | CSF1R (0.46) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28343787 | 0.82 | CSF1R (0.63) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28343625 | 0.81 | CSF1R (0.59) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28343600 | 0.81 | CSF1R (0.58) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28343584 | 0.81 | CSF1R (0.62) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL16028640 | 0.81 | CSF1R (0.56) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28343654 | 0.80 | CSF1R (0.46) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 | |
| SCHEMBL28343606 | 0.80 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBFLT3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228620-B | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | 德西费拉制药有限责任公司 | 2020-09-04 | — | — | CN | claimed |