Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884762 | 0.89 | PPM1B (0.40) | LMNAKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL1397145 | 0.81 | LMNA (0.46) | LMNATSHRPPM1BTBXA2RALDH1A1 | |
| SCHEMBL5703992 | 0.80 | PTGS1 (0.37) | — | |
| SCHEMBL27634295 | 0.80 | LMNA (0.45) | LMNATSHRPMP22NFKB1PPM1B | |
| SCHEMBL27633977 | 0.80 | LMNA (0.45) | LMNATSHRPMP22NFKB1PPM1B | |
| SCHEMBL29148852 | 0.80 | LMNA (0.45) | LMNATSHRPPM1BTBXA2RALDH1A1 | |
| SCHEMBL27634447 | 0.80 | LMNA (0.45) | LMNATSHRPMP22NFKB1PPM1B | |
| SCHEMBL6944058 | 0.79 | PAOX (0.34) | LMNAKDM5AKDM7AKDM4CPHF8 | |
| SCHEMBL887705 | 0.79 | KDM5A (0.34) | LMNAKDM5AKDM7AKDM4CPHF8 | |
| Adipic Acid SCHEMBL30510690 | 0.79 | ITGB3 (0.35) | LMNAKDM5AKDM7AKDM4CPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192898-B2 | Composition for fluorine-containing volume holographic data recording material and fluorine-containing volume holographic data recording media made of same | DAIKIN INDUSTRIES, LTD. (JP) | 2012-06-05 | — | — | US | disclosed |
| US-20100112460-A1 | COMPOSITION FOR FLUORINE-CONTAINING VOLUME HOLOGRAPHIC DATA RECORDING MATERIAL AND FLUORINE-CONTAINING VOLUME HOLOGRAPHIC DATA RECORDING MEDIA MADE OF SAME | UMEDA CENTER BUILDING (JP) | 2010-05-06 | — | — | US | disclosed |