Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28266636 | 0.83 | PTPN1 (0.42) | OPRM1PGAM1OPRD1PTPN2PTPN1 | |
| SCHEMBL28344148 | 0.72 | CYP19A1 (0.45) | OPRM1OPRD1CNR2ALOX5CNR1 | |
| SCHEMBL28877162 | 0.70 | ALOX5 (0.49) | PGAM1GPR84SMPD1ALOX5PTGS2 | |
| SCHEMBL28588510 | 0.66 | CYP19A1 (0.56) | OPRM1PGAM1OPRD1GPR84CNR2 | |
| SCHEMBL1954870 | 0.66 | ALOX5 (0.47) | PGAM1CNR2ALOX5CNR1PTGS2 | |
| SCHEMBL16267321 | 0.64 | ERN1 (0.53) | PGAM1GPR84CNR2CNR1PTPN1 | |
| SCHEMBL28266635 | 0.64 | PTPN2 (0.35) | PTGS2PTPN2PTPN1PTPN11 | |
| SCHEMBL27846985 | 0.63 | APP (0.64) | — | |
| SCHEMBL30528065 | 0.63 | SMPD1 (0.57) | CNR2SMPD1ALOX5CNR1 | |
| SCHEMBL1405908 | 0.63 | SMPD1 (0.57) | CNR2SMPD1ALOX5CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511202-A | Polycyclic polyisocyanate pentenyl acyl phloroglucinol class compound and the preparation method and application thereof | UNIV XIAMEN | 2019-11-29 | — | — | CN | claimed |
| CN-110511202-A | Polycyclic polyisocyanate pentenyl acyl phloroglucinol class compound and the preparation method and application thereof | UNIV XIAMEN | 2019-11-29 | — | — | CN | disclosed |
| CN-110511202-A | Polycyclic polyisocyanate pentenyl acyl phloroglucinol class compound and the preparation method and application thereof | UNIV XIAMEN | 2019-11-29 | — | — | CN | disclosed |
| CN-110511202-A | Polycyclic polyisocyanate pentenyl acyl phloroglucinol class compound and the preparation method and application thereof | UNIV XIAMEN | 2019-11-29 | — | — | CN | disclosed |