Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28841856 | 0.86 | PGAM1 (0.40) | ALOX5PTGS2PGAM1CNR1CNR2 | |
| SCHEMBL28397047 | 0.85 | PGAM1 (0.39) | ALOX5PTGS2CYP3A4HTTNPC1 | |
| SCHEMBL28877162 | 0.82 | ALOX5 (0.49) | ALOX5PTGS2PGAM1 | |
| SCHEMBL168062 | 0.82 | HTT (0.63) | ALOX5PTGS2CYP3A4HTTNPC1 | |
| SCHEMBL28588510 | 0.80 | CYP19A1 (0.56) | ALOX5PTGS2PGAM1CNR1CNR2 | |
| SCHEMBL19433099 | 0.80 | PTGS2 (0.61) | ALOX5PTGS2CYP3A4HTTNPC1 | |
| SCHEMBL19433098 | 0.80 | PTGS2 (0.61) | ALOX5PTGS2CYP3A4HTTNPC1 | |
| SCHEMBL19433103 | 0.80 | PTGS2 (0.61) | ALOX5PTGS2CYP3A4HTTNPC1 | |
| SCHEMBL9743295 | 0.76 | HTT (0.72) | ALOX5PTGS2CYP3A4HTTNPC1 | |
| SCHEMBL8936709 | 0.75 | CNR1 (0.67) | ALOX5PTGS2CYP3A4CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071547-A1 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2013-03-21 | — | — | US | claimed |
| EP-2509452-A2 | LOW CALORIC FAT REPLACERS | Nestec S.A. (CH) | 2012-10-17 | — | — | EP | claimed |
| WO-2011069958-A2 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2011-06-16 | — | — | WO | claimed |
| EP-2332427-A1 | low caloric fat replacers | Nestec S.A. (CH) | 2011-06-15 | — | — | EP | claimed |
| US-20130071547-A1 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2013-03-21 | — | — | US | disclosed |
| EP-2509452-A2 | LOW CALORIC FAT REPLACERS | Nestec S.A. (CH) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069958-A2 | LOW CALORIC FAT REPLACERS | NESTEC S.A. (CH) | 2011-06-16 | — | — | WO | disclosed |
| EP-2332427-A1 | low caloric fat replacers | Nestec S.A. (CH) | 2011-06-15 | — | — | EP | disclosed |
| WO-2007060532-A2 | NOVEL THERAPEUTIC COMPOSITIONS AND METHOD FOR PRODUCING ACTIVE PRINCIPLES | R ET D PHARMA (MC) | 2007-05-31 | — | — | WO | disclosed |