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SCHEMBL28344253

SCHEMBL28344253

CNC(=O)/C(=N/OC)c1ccccc1CON=Cc1cccc(O/C(F)=C\c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 8/20 0.55
▸ MAOB P27338 4/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ ATM Q13315 1/20 0.34
▸ KLF5 Q13887 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28344252 1.00 HIF1A (0.55) HIF1AMAOBHDAC1HDAC2LMNA
SCHEMBL321897 0.89 HIF1A (0.45) HIF1AMAOBLMNAATM
SCHEMBL29408787 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL67325 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL67324 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL15660631 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL19112233 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL67326 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL14508198 0.87 HIF1A (0.53) HIF1ALMNAATM
SCHEMBL15660633 0.87 HIF1A (0.53) HIF1ALMNAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 — — CN disclosed
CN-110678076-A Plant treatment products and related methods 美国赛多美科技有限公司 2020-01-10 — — CN disclosed