SCHEMBL67324

SCHEMBL67324

CNC(=O)/C(=N/OC)c1ccccc1CO/N=C(\C)c1cccc(O/C(F)=C\c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.53
PPARG P37231 4/20 0.35
PPARA Q07869 3/20 0.35
ATM Q13315 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67325 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL15660631 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL29408787 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL15660633 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL14508198 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL19112233 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL67326 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL4592315 0.90 HIF1A (0.43) HIF1AATMLMNAHTTKMT2A
Methyl Alcohol SCHEMBL22204610 0.88 HIF1A (0.41) HIF1APPARGPPARAATMLMNA
SCHEMBL28344253 0.87 HIF1A (0.55) HIF1AATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1682 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384016-B1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AG (DE) 2025-09-03 EP claimed
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2024-11-07 US claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN claimed
US-20240023551-A1 USE OF DHODH INHIBITOR FOR CONTROLLING RESISTANT PHYTOPATHOGENIC FUNGI IN CROPS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-25 US claimed
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 US claimed
US-20230200391-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2023-06-29 US claimed
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed
US-20230133087-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2023-05-04 US claimed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
CN-115955916-A Active compound combinations 拜耳公司 2023-04-11 CN claimed
US-20100311590-A1 METHOD FOR IMPROVING THE BUD QUALITY OF A PLANT BAYER CROPSCIENCE AG (DE) 2010-12-09 US claimed
EP-2255649-A2 Agent combinations Bayer CropScience AG (DE) 2010-12-01 EP claimed
EP-1893024-B1 ACTIVE SUBSTANCE COMBINATIONS BAYER CROPSCIENCE AG (DE) 2010-10-13 EP claimed
EP-2234489-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2010-10-06 EP claimed
US-20100152270-A1 PESTICIDE COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND A FUNGICIDE COMPOUND BAYER INTELLECTUAL PROPERTY GMBH (DE) 2010-06-17 US claimed
WO-2010060982-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2010-06-03 WO claimed
US-20100113278-A1 PESTICIDAL COMPOSITION COMPRISING SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND A FUNGICIDE COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-05-06 US claimed
EP-2148568-A1 METHOD FOR IMPROVING THE BUD QUALITY OF A PLANT Bayer CropScience SA (FR) 2010-02-03 EP claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
WO-2008142029-A1 METHOD FOR IMPROVING THE BUD QUALITY OF A PLANT BAYER CROPSCIENCE SA (FR) 2008-11-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX HIF1A 3913/4885PPARG 3267/4885PPARA 3706/4885
US-20100152270-A1 PESTICIDE COMPOSITION COMPRISING A STRIGOLACTONE DERIVATIVE AND A FUNGICIDE COMPOUND PTMS, THOP1, CYP17A1 HIF1A 4820/4885PPARG 3123/4885PPARA 3572/4885
US-20240023551-A1 USE OF DHODH INHIBITOR FOR CONTROLLING RESISTANT PHYTOPATHOGENIC FUNGI IN CROPS DHODH, SDHA, SDHB HIF1A 672/4885PPARG 3657/4885PPARA 3883/4885
US-20100311590-A1 METHOD FOR IMPROVING THE BUD QUALITY OF A PLANT EBPL, FOSB, FOS HIF1A 2889/4885PPARG 942/4885PPARA 264/4885
US-20230200391-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE ERG28, CYP51A1, ME3 HIF1A 2406/4885PPARG 302/4885PPARA 250/4885
US-20100113278-A1 PESTICIDAL COMPOSITION COMPRISING SYNTHETIC COMPOUND USEFUL AS NODULATION AGENT OF LEGUMINOUS PLANTS AND A FUNGICIDE COMPOUND CYP51A1, LSS, DDT HIF1A 4038/4885PPARG 1996/4885PPARA 2510/4885
US-20240365785-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE DDT, TH, HPD HIF1A 3999/4885PPARG 401/4885PPARA 266/4885
US-20230133087-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE ME3, MT-CO2, MT-CO3 HIF1A 2548/4885PPARG 237/4885PPARA 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.