SCHEMBL19112233

SCHEMBL19112233

CNC(=O)/C(=N/OC)c1ccccc1CON=C(C)c1cccc(O/C(F)=C\c2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.53
PPARG P37231 4/20 0.35
PPARA Q07869 3/20 0.35
ATM Q13315 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL67325 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL15660631 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL29408787 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL15660633 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL14508198 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL67326 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL67324 1.00 HIF1A (0.53) HIF1APPARGPPARAATMLMNA
SCHEMBL4592315 0.90 HIF1A (0.43) HIF1AATMLMNAHTTKMT2A
Methyl Alcohol SCHEMBL22204610 0.88 HIF1A (0.41) HIF1APPARGPPARAATMLMNA
SCHEMBL28344253 0.87 HIF1A (0.55) HIF1AATMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133087-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE BAYER AKTIENGESELLSCHAFT (DE) 2023-05-04 US claimed
CN-115955916-A Active compound combinations 拜耳公司 2023-04-11 CN claimed
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-3473100-A1 ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL/ACARICIDAL PROPERTIES Bayer Aktiengesellschaft (DE) 2019-04-24 EP claimed
US-20250241296-A1 HIGH-LOAD AGRICULTURAL FORMULATIONS AND METHODS OF MAKING SAME BASF CORPORATION (US) 2025-07-31 US disclosed
EP-4384013-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (DE) 2024-06-19 EP disclosed
US-11825838-B2 Tricyclic carboxamides for controlling arthropods BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2023-11-28 US disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed
CN-115955916-A Active compound combinations 拜耳公司 2023-04-11 CN disclosed
CN-115915941-A Pyridine (thio) amides as fungicidal compounds 拜耳公司 2023-04-04 CN disclosed
CN-115885985-A Aqueous suspension concentrates FMC公司 2023-04-04 CN disclosed
US-9832999-B1 Bicyclic compounds as pest control agents BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-12-05 US disclosed
US-20170325459-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-11-16 US disclosed
US-20170325458-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-11-16 US disclosed
US-20170327487-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-11-16 US disclosed
EP-3243387-A2 COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE Bayer CropScience Aktiengesellschaft (DE) 2017-11-15 EP disclosed
US-20170265474-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 US disclosed
US-20170260183-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BRETSCHNEIDER, UTA ANTJE (DE) 2017-09-14 US disclosed
US-9706777-B2 Composition comprising a biological control agent and a fungicide selected from inhibitors of amino acid or protein biosynthesis, inhibitors of ATP production and inhibitors of the cell wall synthesis BAYER CROPSCIENCE AG (DE) 2017-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170265474-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS DDT, BCHE, BAK1 HIF1A 4789/4885PPARG 3050/4885PPARA 3818/4885
US-11825838-B2 Tricyclic carboxamides for controlling arthropods AADAC, FAAH, FAAH2 HIF1A 3383/4885PPARG 2012/4885PPARA 2801/4885
US-20170260183-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS DDT, BCHE, BAK1 HIF1A 4789/4885PPARG 3050/4885PPARA 3818/4885
US-20170325458-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS DDT, BCHE, BAK1 HIF1A 4769/4885PPARG 2937/4885PPARA 3744/4885
US-20170325459-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS DDT, BCHE, BAK1 HIF1A 4789/4885PPARG 3050/4885PPARA 3818/4885
US-20170327487-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS DDT, BCHE, BAK1 HIF1A 4789/4885PPARG 3050/4885PPARA 3818/4885
US-20230133087-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE ME3, MT-CO2, MT-CO3 HIF1A 2548/4885PPARG 237/4885PPARA 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.