Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP12 | P39900 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 4/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24974632 | 0.84 | CES2 (0.50) | MMP9MMP12MMP1MMP2MEN1 | |
| SCHEMBL22296699 | 0.77 | SLC6A2 (0.44) | PDE4APDE4BPDE4CPDE4DPARP10 | |
| SCHEMBL5332916 | 0.74 | MEN1 (0.53) | MMP9MMP12MMP1MMP2MEN1 | |
| SCHEMBL24682363 | 0.74 | PDE4D (0.35) | PDE4APDE4BPDE4CPDE4DPARP10 | |
| SCHEMBL8423858 | 0.73 | MEN1 (0.52) | MMP9MMP12MMP1MMP2MEN1 | |
| Ammonia Solution, Strong SCHEMBL27808056 | 0.73 | MEN1 (0.52) | MMP9MMP12MMP1MMP2MEN1 | |
| SCHEMBL16717449 | 0.72 | PTGS1 (0.42) | MMP9MMP12MMP1MMP2MEN1 | |
| SCHEMBL20944544 | 0.72 | KDM4E (0.49) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL14922550 | 0.72 | MAPT (0.40) | MEN1KMT2A | |
| SCHEMBL30744993 | 0.72 | KDM4E (0.49) | MEN1KMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627770-A | Tetrahydroquinoline compositions as BET bromodomain inhibitors | 福马疗法公司 | 2019-12-31 | — | — | CN | disclosed |