Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM6A | O15550 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | KDM4B | O94953 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944544 | 1.00 | KDM4E (0.49) | KDM4EMKNK1MKNK2PDE4DHTR3A | |
| SCHEMBL20963907 | 0.89 | KDM4E (0.64) | KDM4EMKNK1MKNK2PDE4DPDE4A | |
| SCHEMBL23233760 | 0.84 | KDM4E (0.67) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30744780 | 0.77 | KDM4E (0.50) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL20064223 | 0.76 | KDM4E (0.47) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL30744842 | 0.73 | KDM4E (0.52) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL31134071 | 0.73 | KDM4E (0.41) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL23212187 | 0.73 | KDM4E (0.41) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9050436 | 0.72 | MCHR1 (0.57) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL20554735 | 0.72 | MCHR1 (0.48) | KDM4EMKNK1MKNK2PDE4DPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |